Mounjaro Interactions: Alcohol, Medications, and More

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This article has been written and reviewed for legal accuracy and clarity by Tort Defenders’ writers and staff and is as accurate as possible. This content should not be taken as legal advice from an attorney.

Mounjaro is a weekly injectable drug used to treat type 2 diabetes through improved blood sugar control. It’s part of the glucagon-like peptide-1 (GLP-1) receptor agonist family of medications that doctors recommend using alongside a healthy diet and exercise habits. It is produced by Eli Lilly and was originally approved for use in May 2022.

While there have been extensive clinical trials to prove the safety of Mounjaro, this medication may have adverse reactions when taken with alcohol and other drugs. Patients considering this medication should be aware of these interactions before starting the medication.  

Understanding drug interactions is important for protecting your health. You could potentially avoid negative side effects and severe symptoms because of drug complications. You can also protect yourself legally by researching the recommended medications before taking them to be an informed consumer.     

When To Avoid Mounjaro

The FDA label for Mounjaro lists several specific cases when you would want to avoid this medication. Do not start this injectable medication if: 

  • You have a known allergy to one of the active ingredients or experience allergic reactions like rash or hypersensitivity in your skin after starting the medication. 
  • You are pregnant or may become pregnant, as Mounjaro can cause fetal harm.
  • You have a history of pancreatitis, as Mounjaro has not been studied in this population. 
  • You have type 1 diabetes, as Mounjaro is not designed to support this illness. 
  • You take an oral contraceptive. Patients taking Mounjaro are asked to switch to non-oral methods to prevent pregnancy. 

If you unknowingly fall into one of these groups and take Mounjaro, you may develop serious side symptoms that could have long-term effects or potentially lead to hospitalization. You could potentially make a legal case against the manufacturers of Mounjaro if the medication leaves significant lasting effects or causes financial harm to your household, like medical debt. 

Mounjaro and Alcohol

The National Institute on Alcohol Abuse and Alcoholism cautions Americans against alcohol consumption while on certain medications. According to these experts, “mixing alcohol with certain medications can cause nausea and vomiting, headaches, drowsiness, fainting, or loss of coordination.” 

The effects of alcohol can be more pronounced and severe while you are taking certain drugs. While a single glass of wine might not affect you when you aren’t taking certain medications, it can have significant side effects while on prescribed drugs.  

Studies show that Mounjaro reduces cravings related to both food and alcohol. Patients report a lower desire to drink when they are on this medication. However, most doctors always recommend consuming alcohol in moderation and reducing your alcohol use while taking medication. When in doubt, it’s always best to speak with your healthcare provider. 

Mounjaro Drug Medications

Certain medications are known to have negative interactions with Mounjaro. Talk to your doctor about any medication you are on, and consider how your body might be affected if you take it with Mounjaro. You might be able to prevent negative side effects and complications by choosing other treatment options.  


In most cases, it is not recommended to take insulin and Mounjaro together. The combination of the two medications could cause hypoglycemia, known as low blood sugar. That said, there are some instances when your doctor might recommend both medications. They will carefully adjust the dosage of both your insulin and your Mounjaro to best treat your type 2 diabetes. 

Talk to your doctor if you are prescribed both insulin and Mounjaro but experience hypoglycemia or other negative side effects.    

Birth Control Pills

Your oral contraceptives may be less effective if you take Mounjaro and other GLP-1 medications because they delay gastric emptying. The drugs slow your digestion, which makes you feel fuller for longer. However, this can also impact the absorption of oral birth control hormones. There are even stories of surprise pregnancies online that may have resulted from the interactions between oral birth control and these, or similar, medications. 

Doctors recommend switching birth control methods while on this medication while also using a secondary barrier birth control, like condoms, for extra protection.   

Certain Diabetes Medications

Like insulin, patients who pair Mounjaro with other anti-diabetic medications like Glyburide, Glipizide, and Glimepiride may increase their risk of low blood sugar. Taking Mounjaro alongside these medications can also lead to an increased heart rate, known as tachycardia. 

Oral Medications

Medications that are seemingly unrelated to the management of your type 2 diabetes can be affected by or negatively affect Mounjaro. For example, Warfarin is an oral medication that is used to treat and prevent blood clots. The delayed gastric emptying could affect how this medication is absorbed. 

Other oral medications like Digoxin and Carbamazepine — which are used to treat heart failure and epilepsy, respectively — could also be absorbed less effectively because of Mounjaro.

There are a few steps to safely taking multiple medications at once. Along with carefully following dosage instructions, it’s recommended that you keep a medicine wallet card on hand. This makes it easy to share your medications with other doctors or pharmacists so they can be aware of any negative interactions that could occur when prescribing new treatments. 

Other Interactions

While doctors often focus on the interactions between Mounjaro and other medications, additional lifestyle factors can also impact the effectiveness of this drug. For example, the CDC reports that people with diabetes who smoke “are more likely than those who don’t smoke to have trouble with insulin dosing and with managing their condition.” This is because nicotine raises your blood pressure.

Even the vitamins and supplements you take can interact with Mounjaro and decrease its effectiveness. One of the best things you can do is be transparent with your doctor about any vitamins or supplements you take. Also, discuss dietary changes that could affect your medication. Small changes could have a bigger impact than you realize. 

Legal Implications of Mounjaro Interactions

As of February 2024, there are more than 55 cases against the drugmakers of Ozempic and Mounjaro because of the harsh side effects and complications that result from taking these drugs. Patients are filing class-action lawsuits and mass tort cases to receive compensation for their pain and suffering. It’s likely that the number of these cases will increase.

If you took Mounjaro and experienced negative side effects or unexpected complications, you also might be able to seek compensation with the help of a trusted legal team.   
It’s important to understand any potential drug interactions and issues with the medication you take, whether you are prescribed Mounjaro, Ozempic, or Wegovy. Stay informed and know your rights if your health suffers because of these medications.

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